JNK Promotes Epithelial Cell Anoikis by Transcriptional and Post-translational Regulation of BH3-Only Proteins
Summary: Developmental morphogenesis, tissue injury, and oncogenic transformation can cause the detachment of epithelial cells.These cells are eliminated by a specialized form of apoptosis (anoikis).While the processes that contribute to this form of cell death have been studied, the underlying mechanisms remain unclear.Here, we tested the role of